Registering a domain name is the first step in getting yourself online. If you're starting a new business, it makes sense to choose a business name based on whether the required domain name is available. If you're serious about your business, first look for a .COM. Depending on your country of operation, there are country-level TLDs (Top Level Domains) also available - like .IN for India, .DE for Germany, .CA for Canada, etc. You could also choose from a range of generic TLDs (gTLDs) like .ASIA, .CLUB, etc.
Some country-level TLDs are also used as generic TLDs. For example, .IN (India) is commonly used to denote INternet, .ME (Montenegro) is popularly used for personal blogs.
There are also hundreds of new gTLDs that are being released regularly and are getting popular, due to the diminishing number of .COM domain names available for registration.